I'm left handed, and I have no problems doing most things right handed people have problems with except for writing and eating. If I write, it looks worse than chicken scratch, and eating makes me feel really awkward. I try it a few times to see if I can get better but it just feels too weird for me.
When I was young, I did the sign of the cross after the service ended with my left hand and got hounded for it by parents. Needless to say, I learned at an early age how absurd some superstitions/social mores are!