You'd definitely think so. Our default smilie sprites were originally 64px wide, but on some devices the retina "2x" version looked awful.
Turns out that 64px resized down to 22px looks much worse than 44px (what they are now) resized down to 22px because the scaling multiplier isn't a round number. I guess it's just how some devices render the pixels when there are potentially sub-pixel differences.
That said, which device and browser is this?