As regards commas in particular - they are used as separators in, for example, lists of recipients for Conversations, and so on. They may be similarly used elsewhere, less obvious. So I'd have to guess they may cause some errant system behaviour.
﴾͡๏̯͡๏﴿It's not an issue in general: https://xenforo.com/community/members/﴾͡๏̯͡๏﴿-tk.2537/
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