As the first customer I'm very pleased with all the improvements taking place. As a direct seller of advertisements we are using Revive Adserver (Old name OpenX) for IAB standart click and impression counting. If you are over a few million ad impressions per month I suggest you spend some time with it or DoubleClick For Publishers (From Google). We are not using Adsense but I have experimented with Adsense, this plugin pairing and it works without conflict. Either way, your impression and click counts are standarts compliant for media buying agency business models.
As of now we had no plugin conflict problems but we are not using too many plugins. In my humble opinion I don't think forum owners should customize too much or use too many plugins. Because after a year or two some of customisations will certainly conflict with core updates or other plugins.