not really. in my experience, email is sort of complicated.
smtp is how you send mails through an email client like outlook. if your server offers email services, and you configure an email account for your domain (like
admin@domain.tld) on it, you get smtp details to use for sending mails. pop/imap are for receiving mails. this should logically work fine. check your hosting management panel and see what it offers.
some of us, outsource it to third party services like amazon ses which handle all emails at a cost. amazon ses type services are a safe option but requires a bit more configuration as you first need to connect it to your domain and then configure an email account and get smtp details for entering in xenforo backend.
to get best email delivery experience, there are some other features that needs to be configured like spf, dkim, dmarc. this is sort of easier to do with something like amazon ses. once everything is configured properly, your emails should be safe for delivery. very less chances of them landing in spam folder of your users.
i would suggest testing it with your host's email service first and if it does not work well, exploring amazon ses. it would take a bit of exploring ses to get it configured properly.