If microsoft would have an as-good iPod as Apple, I'd not use iTunes or iPod. But yeah, microsoft cannot beat iPod Shuffle/Nano/Touch/Classic or the iPad xD
I like Spotify much more and am awaiting RDIO
If I hate any application then its apple's Bonjour. Though Quick Time is my pet peeve as well. Quite bizarre to see these and 9 other applications forced on your PC for iTunes.